Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.
Regional Medical Center
1155 Mill St

Children's Hospital
1155 Mill St

Rehabilitation Hospital
1495 Mill St

South Meadows Medical Center
10101 Double R Blvd

Skilled Nursing
1835 Oddie Blvd

Carson Valley Medical Center
1107 HWY 395
Center for Advanced Medicine B
1500 E 2nd St

Center for Advanced Medicine C
75 Pringle Way

Institute for Heart & Vascular Health
1155 Mill St

Institute for Cancer
1155 Mill St
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.
Regional Medical Center
1155 Mill St

Children's Hospital
1155 Mill St

Rehabilitation Hospital
1495 Mill St

South Meadows Medical Center
10101 Double R Blvd

Skilled Nursing
1835 Oddie Blvd

Carson Valley Medical Center
1107 HWY 395
Center for Advanced Medicine B
1500 E 2nd St

Center for Advanced Medicine C
75 Pringle Way

Institute for Heart & Vascular Health
1155 Mill St

Institute for Cancer
1155 Mill St
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Regional Medical Center

1155 Mill St Reno, NV 89502
775-982-4100


Renown Regional Medical Center
1155 Mill St, Reno, NV 89502
Renown Health serves a 17-county region with a total population in excess of 750,000. Our facilities include two medical centers, a rehabilitation hospital, a skilled nursing facility, numerous medical group and urgent care facilities, and the region's most trusted health insurance provider, Hometown Health. 775-982-5000

Renown Children's Hospital

1155 Mill St Reno, NV 89502
775-982-KIDS (5437)

Renown Children's Hospital
1155 Mill St, Reno, NV 89502
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Rehabilitation Hospital

1495 Mill St Reno, NV 89502
775-982-3500


Renown Rebabilitation Hospital - 1495 Mill St
1495 Mill St, Reno, NV 89502
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown South Meadows
Medical Center

10101 Double R Blvd Reno, NV 89521
775-982-7000


Renown South Meadows - 10101 Double R Blvd
10101 Double R Blvd, Reno, NV 89521
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Carson Valley Medical Center

1107 Hwy 395 Gardnerville, NV 89410
775-782-1550


Carson Valley Medical Center - 1107 Highway 395
1107 Highway 395, Gardnerville, NV 89410
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Skilled Nursing

1835 Oddie Blvd Sparks, NV 89431
775-982-3232


Renown Skilled Nursing - 1835 Oddie Blvd
1835 Oddie Boulevard, Sparks, NV 89431
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Health Urgent Care

775-982-5000

Renown Health Urgent Care
9 convenient locations
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.
Renown Lab Services offers convenient access to complete your lab work with 10 locations close to your home or work. For your convenience, many of the locations are located inside or next to Renown hospitals and medical groups. Extended and Saturday hours are available at some locations.
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Center for Advanced Medicine B at Renown Regional

1500 E 2nd St Reno, NV 89502
775-982-4100


Center for Advanced Medicine B - 1500 E. 2nd St
1500 E. 2nd St., Reno, NV 89502
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Center for Advanced Medicine C at Renown Regional

75 Pringle Way Reno, NV 89502
775-982-4100


Center for Advanced Medicine C - 75 Pringle Way
75 Pringle Way, Reno, NV 89502
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Institute Heart & Vascular Health

1155 Mill St Reno, NV 89502
775-982-7888


Institute for Heart & Vascular Health - 1155 Mill St
1155 Mill St, Reno, NV 89502
Based in Reno, Nevada, Renown Health continues to be the regional healthcare leader, serving a 17-county region comprised of northern Nevada, Lake Tahoe and northeast California. Renown is Reno’s only locally owned, not-for-profit health network offering more services than all other local healthcare networks combined.

Renown Institute for Cancer

1155 Mill St Reno, NV 89502
775-982-5638


Renown Institute for Cancer - 1155 Mill St
1155 Mill St, Reno, NV 89502
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Duchenne muscular dystrophy

Definition

Duchenne muscular dystrophy is an inherited disorder that involves muscle weakness, which quickly gets worse.

Alternative Names

Pseudohypertrophic muscular dystrophy; Muscular dystrophy - Duchenne type

Causes, incidence, and risk factors

Duchenne muscular dystrophy is a form of muscular dystrophy that worsens quickly. Other muscular dystrophies (including Becker's muscular dystrophy) get worse much more slowly.

Duchenne muscular dystrophy is caused by a defective gene for dystrophin (a protein in the muscles). However, it often occurs in people without a known family history of the condition.

Because of the way the disease is inherited, boys are affected, not girls. The sons of females who are carriers of the disease (women with a defective gene but no symptoms themselves) each have a 50% chance of having the disease. The daughters each have a 50% chance of being carriers.

Duchenne muscular dystrophy occurs in about 1 out of every 3,600 male infants. Because this is an inherited disorder, risks include a family history of Duchenne muscular dystrophy.

Symptoms

Symptoms usually appear before age 6 and may appear as early as infancy. They may include:

  • Fatigue
  • Learning difficulties (the IQ can be below 75)
  • Intellectual disability (possible, but does not get worse over time)
  • Muscle weakness
    • Begins in the legs and pelvis, but also occurs less severely in the arms, neck, and other areas of the body
    • Difficulty with motor skills (running, hopping, jumping)
    • Frequent falls
    • Trouble getting up from a lying position or climbing stairs
    • Weakness quickly gets worse
  • Progressive difficulty walking
    • Ability to walk may be lost by age 12, and the child will have to use a wheelchair
    • Breathing difficulties and heart disease usually start by age 20

Signs and tests

A complete nervous system (neurological), heart, lung, and muscle exam may show:

  • Abnormal heart muscle (cardiomyopathy)
  • Congestive heart failure or irregular heart rhythm (arrhythmias) -- rare
  • Deformities of the chest and back (scoliosis)
  • Enlarged muscles of the calves, buttocks, and shoulders (around age 4 or 5). These muscles are eventually replaced by fat and connective tissue (pseudohypertrophy).
  • Loss of muscle mass (wasting)
  • Muscle contractures in the heels, legs
  • Muscle deformities
  • Respiratory disorders, including pneumonia and poor swallowing, with food or fluid passing into the lungs (in late stages of the disease)

Tests may include:

Treatment

There is no known cure for Duchenne muscular dystrophy. Treatment aims to control symptoms to improve quality of life.

Steroid drugs can slow the loss of muscle strength. They may be started when the child is diagnosed or when muscle strength begins to decline.

Other treatments include:

  • Albuteral--a drug used for people with asthma
  • Amino acids
  • Carnitine
  • Coenzyme Q10
  • Creatine
  • Fish oil
  • Green tea extracts
  • Vitamin E

However, the effects of these treatments have not been proven. Stem cells and gene therapy may be used in the future.

Activity is encouraged. Inactivity (such as bedrest) can make the muscle disease worse. Physical therapy may be helpful to maintain muscle strength and function. Speech therapy is often needed.

Other treatments may include:

  • Assisted ventilation (used during the day or night)
  • Drugs to help heart function, such as angiotensin-converting-enzyme inhibitors, beta-blockers, and diuretics
  • Orthopedic appliances (such as braces and wheelchairs) to improve mobility
  • Proton pump inhibitors (for people with gastroesophageal reflux)

Several new treatments are being studied in trials.

Support Groups

You can ease the stress of illness by joining a support group where members share common experiences and problems. See muscular dystrophy - support group. The Muscular Dystrophy Association is an excellent source of information on this disease.

Expectations (prognosis)

Duchenne muscular dystrophy leads to quickly worsening disability. Death usually occurs by age 25, typically from lung disorders.

Complications

  • Cardiomyopathy
  • Congestive heart failure (rare)
  • Deformities
  • Heart arrhythmias (rare)
  • Mental impairment (varies, usually minimal)
  • Permanent, progressive disability
    • Decreased mobility
    • Decreased ability to care for self
  • Pneumonia or other respiratory infections
  • Respiratory failure

Calling your health care provider

Call your health care provider if:

  • Your child has symptoms of Duchenne muscular dystrophy
  • Symptoms worsen, or new symptoms develop, particularly fever with cough or breathing difficulties

Prevention

Genetic counseling is advised if there is a family history of the disorder. Duchenne muscular dystrophy can be detected with about 95% accuracy by genetic studies performed during pregnancy.

References

Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Muscular dystrophies. In: Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa:Saunders Elsevier; 2007:chap 608.


Review Date: 2/1/2012
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Assistant Professor of Pediatrics, University of Washington School of Medicine; and Benjamin Seckler, MD, Diagnostic Radiologist, Poughkeepsie, NY, and President of Charley's Fund; and Luc Jasmin, MD, PhD, Department of Neurosurgery at Cedars-Sinai Medical Center, Los Angeles, and Department of Anatomy at UCSF, San Francisco, CA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.
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