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Renown Rheumatology's Comprehensive Approach to Rheumatic Diseases

The board-certified rheumatologists at Renown Rheumatology provide state-of-the art care for a wide range of autoimmune rheumatic diseases such as rheumatoid arthritis, psoriatic arthritis, lupus, Sjogren syndrome, vasculitis, gout, and many more. We use the most advanced evidence-based diagnostic and therapeutic measures to restore health and enhance well-being.

Common Diagnostic Studies Used in the Evaluation of Rheumatic Diseases

  • RF (Rheumatoid Factor): Confers nonspecific risk of rheumatoid arthritis.
  • ACPA (Anti-Citrullinated Protein Antibody): Confers specific risk of rheumatoid arthritis.
  • ANA (Anti-Nuclear Antibody): Confers nonspecific risk of connective tissue disease.
  • ANCA (Anti-Neutrophil Cytoplasmic Antibody): Confers risk of small vessel vasculitis.
  • APLA (Anti-Phospholipid Antibody): Confers risk of antiphospholipid syndrome.
  • C3 and C4 (Complement proteins 3 and 4): Low levels suggest active disease in lupus or related autoimmune diseases.
  • UPCR (Urine Protein-to-Creatinine Ratio): High levels suggest active lupus nephritis or small vessel vasculitis.
  • Uric acid: Elevated in people with gout but may be low during acute gout attack.
  • ESR (Erythrocyte Sedimentation Rate): Nonspecific indicator of chronic inflammation.
  • CRP (C-Reactive Protein): Nonspecific indicator of acute inflammation.
  • CBC (Complete Blood Count): Used to assess the effects of autoimmune diseases and immunosuppressive medications on bone marrow function.
  • CMP (Complete Metabolic Profile): Used to assess the effects of autoimmune diseases and immunosuppressive medications on kidney and liver functions.
  • HLA-B27 (Human Leukocyte Antigen B27): Confers risk of spondyloarthropathy.
  • HLA-B51 (Human Leukocyte Antigen B51): Confers risk of Behcet’s disease.
  • Musculoskeletal Ultrasound: Used at point of care to assess joint inflammation, guide joint injection or joint fluid aspiration.
  • XR: Used to assess joint damage from inflammation or wearing over time.
  • CT or MRI: Used to assess joint, muscle, and blood vessel inflammation which are not visualizable on plain XR.
  • Synovial Fluid Cytology: Used to test for crystals and blood cells in inflamed joints.
  • Synovial Fluid Gram Stain and Culture: Used to test for infection in inflamed joints.

Rheumatic Diseases and Conditions Evaluated by Rheumatologists

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