RENOWN NEWSROOM

Clinical researchers with the Healthy Nevada Project co-author research paper with findings that emphasize the need for a comprehensive approach to breast cancer risk assessment – including a focus on genetic medicine – to help ensure that individuals at high risk are identified and supported proactively rather than reactively.  Breast cancer is a leading cause of cancer death among women in the United States. According to the American Cancer Society, about 1 in 8 women will develop breast cancer and about 1 in 39 women will die from breast cancer. Breast cancer is associated with increased age, hereditary factors, obesity, and alcohol use. Since 1990, breast cancer death rates have declined progressively due to advancements in treatment and detection. In Nevada there are an estimated 2,310 new breast cancer cases a year, and genetic mutations such as in the genes BRCA1 or BRCA2 remain a top risk factor for this prevalent disease. Recognizing the urgency for progress in breast cancer research, a collaborative effort between physicians, advanced practice providers and scientists from the Healthy Nevada Project® (HNP) and Helix have unveiled groundbreaking research. This study explores how genetic screenings are a necessary supplement to traditional testing methods, together offering more accurate insights into a patient's likelihood of developing breast cancer in the future. HNP is operated by Renown Genomic Medicine and the Institute for Health Innovation and is one of the largest community-based population health studies in the country. Their team works in collaboration with Helix, a leader in precision health that delivers comprehensive genomic solutions. Together, this dynamic partnership aims to understand breast cancer risk factors and pave the way for more effective preventative measures. The combined research team studied 25,591 female HNP participants to evaluate the performance of different genetic screening approaches to identify women at high risk of breast cancer. The results of this research suggest that a combined monogenic, or single-gene, and polygenic, or multi-gene, approach to breast cancer screenings helped produce more accurate results and more closely identify study participants who have a high genetic risk of developing the disease. "Based on this research, we are advocating a shift in approach which would improve breast cancer risk assessment through a combination of effective family history ascertainment and genetic screening,” said Joseph Grzymski, PhD, principal investigator of the Healthy Nevada Project, research professor at the University of Nevada, Reno School of Medicine and co-author of the breast cancer research paper. “This tailored approach, founded on the assessment of individual genetic risk, not only intends to elevate patient well-being but also will improve efficiency and equity in healthcare." Complementing the team’s research on leveraging genetics to identify women at low genetic risk of breast cancer that could safely defer mammogram screenings by five to 10 years that was released in late 2023 in JAMA Oncology, the study suggests that incorporating genetic information can assist in personalizing breast cancer screenings and optimizing the use of screening resources. "Existing disparities persist across various facets of breast cancer screening and treatment; however, genetic screening is clearly a powerful tool to help facilitate early intervention for those at higher risk,” said Jamie Schnell Blitstein, APRN, a primary care nurse practitioner at Renown Health and co-author of the breast cancer research paper. “By placing a heightened focus on risk, we underscore the pivotal role of preventative breast cancer screening.” Despite the availability of effective methods for early screening, co-authors of this research found that 78 percent of women with a family history of breast cancer had their risk ascertained only after a breast cancer diagnosis. The findings emphasize the need for a comprehensive approach to breast cancer risk assessment – including a focus on genetic medicine – to help ensure that individuals at high risk are identified and supported proactively rather than reactively.  “These findings that can profoundly impact how healthcare is delivered were only made possible by all the participants who were willing to consent to research,” said Alex Bolze, PhD from Helix and co-author of the publication. “Broad-scale collaboration projects like these between Renown Health and UNR that engage large populations where participants share both their genetic information as well as electronic health records drive advancements in preventative medicine, as well as fundamental biological research.”   The research paper was officially accepted on Jan. 29, 2024, and will be published by Elsevier, Inc. on behalf of the American College of Medical Genetics and Genomics. The contents of the paper will appear in the international journal Genetics in Medicine Open. Read the full article by visiting sciencedirect.com. The Healthy Nevada Project is currently recruiting new study participants. Free to all Nevadans with a saliva sample or blood draw, participants and their referring providers receive access to whole-exome sequencing and clinical grade results that help provide insight into their unique genetic risks tied to heart disease and certain cancers. If you are interested in enrolling in the study, schedule a Virtual Consent Appointment through MyChart or contact the Renown Institute for Health Innovation at RenownIHI@renown.org or (775) 982-6914 to be connected to a Genomic Representative. About Renown Health Renown Health is the region’s largest, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the region’s largest, locally owned not-for-profit insurance company, Hometown Health. Renown is currently enrolling participants in the largest community-based genetic population health study, the Healthy Nevada Project®. To join the Renown Health team, visit renown.org/careers. About Helix Helix is the leading population genomics and viral surveillance company operating at the intersection of clinical care, research, and data analytics. Helix enables health systems, life sciences companies, payers, and government partners to accelerate the integration of genomic data into patient care and public health decision-making. Learn more at helix.com.

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Renown Children’s Hospital and Children’s Miracle Network Hospitals (CMNH) are excited to announce Shaylie Edwards as the 2023 Champion Child. A fighter from a young age, seven-year-old Shaylie has overcome many challenges in her short life. In 2019 when she was three, Shaylie was hit by a car while using a crosswalk with her father. She was admitted to the Wilbur D. May Pediatric Intensive Care Unit (PICU) at Renown Children’s Hospital and stayed there for three months. A video introducing Shaylie and her journey can be found here.  Shaylie’s mom, Erica Edwards reports that as a result of the accident, Shaylie has been treated by Renown Children’s Hospital physicians, nurses and team for a broken neck in two places, a broken jaw in two places, a fractured sacrum, a broken femur and three small brain bleeds. She has been in outpatient therapy for the last three years and continues making strides daily. “Shaylie’s perseverance, dedication and joy inspires all of us at Renown Children’s Hospital,” said Kristina Deeter, MD, MBA, FAAP Physician-in-Chief, Renown Children’s Hospital and Chair of Pediatrics, University of Nevada, Reno School of Medicine,” (pictured right with Shaylie). “It has been an incredible joy to witness her progress and to care for Shaylie and her family. We are thrilled she has been chosen to share her story with the world.”  The New England Journal of Medicine cites preventable injuries as the number one leading cause of death among children. This includes motor vehicle accidents, firearm injuries, drowning, poisoning, burns and suffocation. According to Safe Kids Worldwide, an average of 155 children under the age of 10 die every year as a result of pedestrian injury, with 64% of those involving motor vehicles. Across the U.S., due to distracted driving, a pedestrian is killed every two hours and injured every seven minutes. Most drivers feel they can safely take their eyes off the road for 0-2 seconds, but a car can travel the length of a football field in 5 seconds at 55 MPH. Shaylie’s family and the team at Renown Children’s Hospital urge drivers to be fully aware and eliminate distractions while driving.  “We were in the Wilbur D. May PICU for three months and the first five days were very iffy. We did not know if she would come out of her coma, but Shaylie is a fighter. The care team at Renown Children’s Hospital made me feel at home and like we were all going through this together,” said Shaylie’s mother, Erica Edwards. “Shaylie’s recovery was a collaboration between doctors, nurses, and our family. Together we were there to support Shaylie, who has proven to us repeatedly that she has a greater purpose in life.” “It was heartwarming to meet Shaylie and her family,” said Dr. Brian Erling, MBA, CEO of Renown Health. “Shaylie is truly a champion! She and her family have faced life's unanticipated events with strength and resilience. Despite the struggles, they have carried on with hope and determination. They find joy in life every day and inspire us all. We have much to learn from their example.” Through Renown Children’s Hospital, Shaylie and 100,000 area children now have access to more than 60 pediatricians, including those specializing in adolescent medicine; anesthesia; cardiology; craniofacial surgery; dentistry; ear, nose and throat conditions; emergency medicine; endocrinology; gastroenterology;  general pediatrics; hospitalist medicine; intensive care; neonatology; neurology; oncology; ophthalmology;  orthopedics; psychiatry; psychology; pulmonology; surgery; urology and other subspecialties previously lacking in the community, as well as a pediatric emergency room, pediatric ICU and contemporary healthcare services at Renown Children’s Hospital. Prior to 2016, about 30% of all pediatric patients had to leave northern Nevada to receive the specialty care they needed. Now, thanks to donor support, Renown estimates that 97% of all pediatric patients and their families can receive both general and specialty pediatric care locally. The next nearest children’s hospital in the state is 7 hours or 438 miles away in Las Vegas. Renown Children’s Hospital is proud to be the only CMNH hospital in northern Nevada, one of only 170 premier children’s hospitals in North America. Shaylie will serve as Renown Children’s Hospital’s CMNH Champion Child for the next year, shining as the face of the hospital in the community and sharing her inspiring story. Renown Health Foundation oversees the local CMNH programs and its fundraising. One hundred percent of all funds raised by CMNH partners stay local to support children and families in our community. Your generous support affords much-needed items to help our littlest patients cope with the potential stressors associated with hospitalization and illness. To donate, visit www.renown.org/donate. About Renown Health Renown Health is Nevada’s largest, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe, and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination, and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the locally owned not-for-profit insurance company, Hometown Health. Renown is hiring people like you. Visit us at www.renown.org/careers.  About Children’s Miracle Network Hospitals Children’s Miracle Network Hospitals® raises funds and awareness for 170 member hospitals that provide 32 million treatments each year to kids across the U.S. and Canada. Donations stay local to fund critical treatments and healthcare services, pediatric medical equipment, and charitable care. Since 1983, Children’s Miracle Network Hospitals has raised more than $7 billion, most of it $1 at a time through the charity's Miracle Balloon icon. Its various fundraising partners and programs support the nonprofit's mission to save and improve the lives of as many children as possible. Find out why children's hospitals need community support, and learn about your member hospital, at www.renown.org/CMNH.

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Rainbow lights illuminate Renown’s iconic “LOVE” sculpture, and powerful employee stories shared during Pride Month. Reno, Nev. (June 16, 2020) –In celebration of Pride Month and Reno’s LGBTQ+ communities, Renown’s LOVE sculpture, a one-ton, welded aluminum artwork with letters 10-feet tall and eight-feet wide, will be illuminated by rainbow LED lights throughout the month of June. LOVE is located at Renown Regional Medical Center’s main entrance at 1155 Mill Street in Reno, Nev. and visible to vehicular and pedestrian traffic along the Mill Street and Ryland Street corridors. Dr. Tony Slonim, president and CEO of Renown says, “At Renown, we are proud to support our LGBTQ+ communities. During Pride Month and beyond, we are honored to offer an inclusive, safe environment for our staff and patients—one that celebrates diversity in all its forms. The LOVE sculpture has already brought a bright light into our world, and I look forward to the joy it will bring to everyone who gets to see it in rainbow colors.”    In commemoration of Pride Month, Renown is committed to highlighting some of the LGBTQ+ individuals who make up a portion of its 7,000 employees. Sean Savoy, Renown’s manager of spiritual care, shares how his experiences as a gay man positively affect his career in spiritual healing and the compassion he shows others.     "The foundation of spiritual care is compassion – being with people in need by caring, supporting, and showing empathy, and promoting a sense of well-being,” said Savoy. Being a member of the LGBTQ+ community informs that deep sense of compassion and empathy in a very special and unique way.I have found the intersectionality of my gay and spiritual selves has been a blessing in my life."  Created by artist Laura Kimpton and fabricated by Jeff Schomberg, the LOVE sculpture first appeared at Burning Man in 2019. Thanks to a partnership with non-profit Artown, the sculpture debuted at Renown in April of 2020, and since served as a symbol of hope and determination for hospital staff, patients and community members amid the COVID-19 pandemic. Generous donors and the Renown Health Foundation funded the sculpture’s instillation.   ###   About Renown Health  Renown Health is a locally governed and locally owned, not-for-profit integrated healthcare network serving northern Nevada, Lake Tahoe and northeast California. Renown is one of the region’s largest private employers with a workforce of more than 7,000. It comprises three acute care hospitals, a rehabilitation hospital, the area’s most comprehensive medical group and urgent care network, and the region’s largest and only locally owned not-for-profit insurance company, Hometown Health. Renown has a long tradition and commitment to continually improve the care and the health of our community. For more information, visit renown.org. Media Contact: Public Relations M: 775-691-7308 E: news@renown.org

Read More About Renown Celebrates Pride Month and LGBTQ+ Communities with Love