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The study could expand to a quarter million people, making Nevada the only state in the U.S. to offer such a program. Las Vegas, Nev. (May 2, 2019) – The Healthy Nevada Project, a first-of-its-kind, community-based population health study combining genetic, clinical, environmental and social data, is expanding enrollment to Las Vegas. The Project aspires not only to offer genetic testing to every Nevadan interested in learning more about their health and genetic profile but ultimately, to develop and expand the Project for communities across the United States to drive positive health outcomes nationwide.   Adding 25,000 Study Volunteers in Southern Nevada The Healthy Nevada Project is announcing a statewide expansion – opening 25,000 testing slots in Las Vegas. With southern Nevada welcoming the study, the Healthy Nevada Project will offer no-cost genetic testing through a simple spit sample to 25,000 study volunteers. Study volunteers will take Helix’s clinical-grade DNA saliva test and will receive their ancestry and traits, at no cost, through the My Healthy Nevada Traits app. Participants will then be given a chance to answer a follow-up health survey from Renown Institute for Health Innovation (Renown IHI), and upon survey completion, will be entered to win an iPhone. In addition, study participants can agree to be notified about genetic test results that could impact their health, and which could be used to improve their medical care. This return of clinical results, plus genetic counseling and other genetic services as appropriate, will be provided by Genome Medical, the leading network of clinical genetics specialists.   Healthy Nevada Project’s Evolution & Ongoing Expansion With more than 35,000 study participants enrolled in just over two years, the Healthy Nevada Project has become the fastest-enrolling genetic study in the country. The Project was created by Renown IHI – a collaboration between Reno, Nev.-based not-for-profit health network, Renown Health, and the world leader in environmental data, Desert Research Institute (DRI). Leveraging Renown’s forward-thinking approach to community health care and DRI’s data analytics and environmental expertise, Renown IHI has grown its capabilities to lead a larger, more complex research study of significance that will analyze and model public health risks in Nevada and serve as a national model for future population health studies working to improve overall health through clinical care integration. During the Project’s pilot launch in September 2016, more than 10,000 community members signed up for DNA testing in just 48 hours. In March 2018, phase two offered full genomic sequencing through a simple spit test from Helix to northern Nevadans. In October 2018, the Project announced the return of clinical results for study participants, notifying them of their risk for CDC Tier 1 conditions including familial hypercholesterolemia, BRCA positive 1 and 2, and Lynch syndrome, a precursor to colon cancer. These conditions affect more than one percent of the population and are inherited so they impact family members as well. Now, the Project announced its next phase – expanding enrollment to 25,000 people in southern Nevada.   Serving as a National Model This expansion to Las Vegas truly makes this the “Healthy Nevada Project” with a statewide impact making Nevada the only state in the U.S. to offer such a program. “Nevada was ripe to advance population health goals because, sadly, our state ranks near the bottom in health outcomes. The Healthy Nevada Project is working to change that,” said Anthony Slonim, M.D., DrPH, FACHE, president and CEO of Renown Health and president of Renown IHI. “Our researchers are working on a number of clinical programs and scientific studies to determine why in Washoe County, the county in which Renown Health is located, Nevada’s age-adjusted death rates for heart disease, cancer and chronic lower respiratory disease are 33 percent higher than the national rate. Imagine if we can gather more data like this on a national scale and use it to change the future of health and health care? That is what the Healthy USA Project is looking to do in the years to come.” “The Healthy Nevada Project is committed to providing study participants clinically actionable data that will help improve their health,” said Joseph Grzymski, Ph.D., associate research professor at DRI, principal investigator of the Healthy Nevada Project and chief scientific officer for Renown Health. “We are providing this information at the individual level so study volunteers can make lifesaving changes to reduce their risk. We’re also doing it on the community level to develop leading-edge research on health determinants for entire neighborhoods, states and eventually, the country.”   Expanding to Become the Healthy USA Project The accelerated speed of the Project is made possible thanks to the ever-decreasing cost of sequencing. Today, Helix is able to sequence an entire exome – which allows reporting on most actionable genomic knowledge – for a fraction of what it would have cost just 10 years ago. Additionally, advances in digital health mean Helix and Project researchers can capture unprecedented amounts of health data digitally, making significant contributions to advancing precision health. The partnership has managed to remove the traditional barriers of population health studies, including the difficulty in recruiting participants, establishing quality high through put lab systems, and scaling interpretation and return of results. This development will be key as other health systems around the country join the Project. “We are thrilled to see the constant, fast-paced evolution of this Project with Renown IHI,” said Justin Kao, CoFounder of Helix. “In less than a year, we have sequenced the DNA of thousands of study participants and are now preparing to offer this incredible study in other states. Combining environmental, clinical, social and genetic data allows us to discover risk factors within communities and help people take action to live longer, healthier lives. That’s what makes the next step of the Healthy USA Project so exciting for all of us. ”Full details on study’s evolution and southern Nevada enrollment will be revealed at a press event in Las Vegas on Tuesday, May 7 at 3 p.m.     Renown Institute for Health Innovation  Renown Institute for Health Innovation is a collaboration between Renown Health - a locally governed and locally owned, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California; and the Desert Research Institute - a recognized world leader in investigating the effects of natural and human-induced environmental change and advancing technologies aimed at assessing a changing planet. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Learn more at https://healthynv.org/.  Helix is a genomics company with a simple but powerful mission: to empower every person to improve their life through DNA. Our affordable, turnkey population health solution enables institutions to quickly scale projects that engage communities and accelerate research and discovery, ultimately allowing every person to benefit from the power of genomics. We've also created the first marketplace for DNA-powered products where people can explore diverse and uniquely personalized products developed by high-quality partners, providing powerful tools to increase engagement and speed the pace of population-scale genomics. Helix is headquartered in the San Francisco Bay Area, has an office in Denver, Colorado and operates a CLIA-certified and CAP-accredited next-generation sequencing lab in San Diego powered by Illumina (NASDAQ: ILMN) NGS technology. Helix was created in 2015. Learn more at www.helix.com.  Helix, the Helix logo and Exome+ are trademarks of Helix Opco, LLC. All other trademarks referenced herein are the property of their respective owners.   Additional Media Contacts: Tracy Bower                                                                                                                                                                          DRI                                                                                                                                                                                      702-862-5404                                                                                                                                                      media@dri.edu Eric Schubert                                                                                                                                                                        Seismic for Helix                                                                                                                                                                    415-939-4366                                                                                                                                                    press@helix.com

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Renown Health is excited to announce a hopeful moment to start the new year with the first baby of 2021. Jessa Mae Estrada, 26, of Reno gave birth to baby Oli Amelia Estrada at 3:59 a.m. on Jan. 1, 2021. Baby Oli weighed 5 pounds, 14.4 ounces and was the first 2021 birth at any of the region’s hospitals.  “Baby Oli’s birth serves as a beautiful symbol of hope for all of us as we look forward to brighter days ahead full of joy, promise and new beginnings,” said Tony Slonim, MD, DrPH, Renown’s President and CEO. “As we take time to reflect on the many challenges and uncertainties brought on in 2020, I will never forget the steadfast determination and resilience demonstrated by our entire community. For it is our collective ability to overcome adversity that makes celebratory moments like these even more meaningful.”  Baby Oli is welcomed to the world by her father, Oliver Estrada, siblings Nate, 2, and Naz, 1, and grandparents Charito and Eduardo Estrada. “I am excited to welcome our first baby of 2021 and celebrate this joyful moment,” said Larry Duncan, Vice President of Pediatrics and Surgery and Administrator, Renown Children's Hospital. “I want to wish all of the new parents the best and make sure they know Renown is here to provide the quality care the families in our community deserve.” More than 4,000 babies are delivered each year at Renown Regional Medical Center. Renown Children’s Hospital has a Neonatal Intensive Care Unit (NICU), and the region’s only Children’s ER and Pediatric ICU, and is the only hospital affiliated with Children’s Miracle Network Hospitals (CMNH) in the region.  Please see the above photo for you to share showing the healthy and happy, mom and baby.  About Renown Health Renown Health is the region’s largest, locally owned and governed, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the region’s largest, locally owned not-for-profit insurance company, Hometown Health. Renown’s institute model addresses social determinants of health a1nd includes: Child Health, Behavioral Health & Addiction, Healthy Aging and Health Innovation. Clinical institutes include: Cancer, Heart and Vascular Health, Neurosciences and Robotic Surgery. Renown is currently enrolling participants in the world’s largest community-based genetic population health study, the Healthy Nevada Project®. For more information visit, renown.org.

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Renown Children’s Hospital pediatric ophthalmologist Dr. Mitchell Strominger hosts state-wide virtual event to provide routine vison screenings for children and Walk with a Doc. Renown Children’s Hospital pediatric ophthalmologist Dr. Mitchell Strominger is set to host a virtual Walk with a Doc event on Sunday, June 14 at 10 a.m. for elementary school children and their parents. During this free event, Dr. Strominger will give a brief, kid-friendly talk about the importance of routine vision screenings and show parents how to conduct a vision screening with their kids at home. He will close out the morning session with a live Q&A. Following the event, families are encouraged to get outside and enjoy a walk in the great outdoors. The event is sponsored by Renown Children’s Hospital and free to participants, however you must register to receive the link to attend. “Vision is important for learning, experiencing new things and interacting with others, which is why it’s critical for children to get vision screenings early and routinely,” said Dr. Strominger. “The best time to screen a child’s vision is kindergarten through third grade as the cells in the brain responsible for vision are continuously developing up until age eight. If we detect vision problems early, we here at Renown Children’s Hospital have the expertise and technology to correct these vision problems and enable children to live healthy, productive lives.” Individuals who register for this event will be emailed a vision-screening sheet to help facilitate an at-home screening, as well as a form to send back to their child’s pediatrician or pediatric ophthalmologist upon completion to determine the best course of action. Dr. Strominger added, “Many parents and schools have put off vision screenings due to COVID- 19 school closings, hesitations of safely leaving their homes or potential financial costs. I am pleased to host this virtual event on behalf of Renown Children’s Hospital, to engage kids and parents in a conversation on the importance of vision and to remind the community that we are here to help and provide the care they need, both in-person and virtually—be it over a smart phone, tablet or computer screen.” This virtual event will take place in the newly renovated Fianna’s Healing Garden which re-opens later this month and has been funded 100% by donations through the Renown Health Foundation. Located in the heart of Renown Regional Medical Center, the healing garden serves as place to enjoy the serenity and beauty of the outdoors. Dr. Strominger is one of 26 pediatric subspecialists recruited to Renown Children’s Hospital since 2016, thanks to the Pennington Foundation's $7.5 million donation made to the non-profit Renown Health Foundation to expand children’s health services. June marks the four-year anniversary of the Nevada Chapter of the American Academy of Pediatrics’ (Nevada APP) participation in the national Walk with A Doc event. Dr. Strominger is the secretary and treasurer for the Nevada AAP. From pediatric specialties, 24/7 ER care and surgery, to imaging, pediatric ICU and child life specialists, Renown Children’s Hospital is dedicated to helping kids feel welcome, safe and well cared for. Through each visit, parents can expect the highest level of care for their child’s health and well-being from birth and beyond. To support Renown Children’s Hospital and help local children in need get access to vital health services like routine vision screenings, please visit the Renown Health Foundation.     About Renown Health Renown Health is a locally governed and locally owned, not-for-profit integrated healthcare network serving northern Nevada, Lake Tahoe and northeast California. Renown is one of the region’s largest private employers with a workforce of more than 7,000. It comprises three acute care hospitals, Renown Children’s Hospital, Renown Rehabilitation Hospital, the area’s most comprehensive medical group and urgent care network, and the region’s largest and only locally owned not-for-profit insurance company, Hometown Health. Renown has a long tradition and commitment to continually improve the care and the health of our community. For more information, visit renown.org.

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Two pediatric gastroenterologists bring life-saving care to kids and make Renown their new home The Renown Children’s Hospital team and our community is celebrating the addition of a new life-saving pediatric specialty to its practice serving children and families in northern Nevada. Parents and guardians will now be able to seek professional pediatric gastroenterologist care with the addition of Drs. Juan Gregory and Kathleen Holland to Renown Medical Group. “Recognizing the importance of diagnosing and caring for children who have conditions that affect the organs in the digestive system, including the stomach, liver and bowel, while also helping children who have issues feeding and eating, is critically important to us at Renown,” said Kristina Deeter, MD, MBA, FAAP, Chair of Pediatrics, University of Nevada Reno School of Medicine (UNR Med) and Physician-in-Chief, Renown Children’s Hospital. “Both Drs. Gregory and Holland are superb clinicians, we are excited to have them join Renown Children’s Hospital to offer pediatric gastroenterology services, including a wide range of complex and vital procedures and screenings, endoscopies and colonoscopies.” Juan Carlos Gregory, MD, has 18 years of experience caring for children in northern Nevada. He is a clinical associate professor of pediatrics at UNR Med with a special interest in celiac disease, abdominal pain, and gastroesophageal reflux in children. Gregory earned his undergraduate degree at Texas Christian University in Fort Worth, TX before completing his medical training, including a residency in pediatrics at the University of San Diego in Pediatrics and fellowships in Pediatric Gastroenterology and Nutrition at both Children’s National Medical Center in Washington, DC, and at the National Institutes of Health, Digestive Disease Section in Bethesda, MD. He is board-certified in Pediatric Gastroenterology and speaks Spanish. Kathleen Holland, MD, MPH brings a global health perspective to her work caring for children. A graduate of the University of Nevada Reno School of Medicine (UNR Med) with her medical doctorate and her master’s in public health with a social and behavioral health emphasis, she has donated her skills to providing international medical relief for children in Uganda and Nicaragua. Holland earned her undergraduate degree at University of Nevada Reno in Biology, Health Ecology and Healthcare Ethics before completing her medical training and residency in Pediatrics and a fellowship in Pediatric Gastroenterology at Indiana University School of Medicine in Indianapolis, IN. Her research and scientific interests include vaccination rates and family barriers among children with inflammatory bowel disease, Crohn’s and colitis, pediatric autoimmune pancreatitis, and cystic fibrosis. How Pediatric Gastroenterologists Help Children and Families The Pediatric Gastroenterology Program at Renown Children’s cares for children experiencing common GI-related problems of childhood; nausea, vomiting, abdominal pain, diarrhea, constipation, reflux, colic, milk protein allergy, poor growth and feeding difficulties, and sees patients from infancy to 18 years old. “As specialists in the care of children with gastrointestinal and liver problems, we focus on the diagnosis and treatment of these issues,” said Larry Duncan, MD, Vice President of Pediatrics and Surgery & Administrator of Renown Children’s & Women’s Services. “Our physicians play an active role in teaching and research. We have several areas of expertise including prevention, diagnosis and treating disease of the digestive tract including the esophagus, gallbladder, stomach, pancreas, colon, small intestine and liver disease.” Special expertise includes: Pediatric feeding and growing disorders Aerodigestive disorders Food and hypersensitivity disorders Inflammatory bowel disease Celiac disease Liver diseases Children requiring parenteral and enteral nutrition Renown Children’s Hospital is the only dedicated children’s hospital in northern Nevada, offering programs and services for families from a 100,000 square mile area, from Sacramento, CA to Salt Lake City, Utah. Renown Children’s provides the area’s only Children’s Emergency Room, Pediatric ICU (PICU), children’s imaging center and the largest neonatal ICU (NICU), a level III intensive care unit. Specialty Children’s Care at Renown Today, over 90% of families in northern Nevada seek care from the experts at Renown Children’s Hospital. “We are so grateful to the William N. Pennington Foundation for its support in establishing the William N. Pennington Fund for Advance Pediatric Care in 2016, which allowed us to hire our first 15 pediatric specialists,” said Dr. Deeter. “Today we have over 40 pediatric physician specialists at Renown Children’s Hospital who provide care in adolescent medicine, pediatric endocrinology, pediatric hematology/oncology, pediatric pulmonology, pediatric neurology, pediatric nephrology, pediatric infectious diseases, pediatric ophthalmology, pediatric orthopedic surgery, pediatric cleft and craniofacial surgery, pediatric urology, pediatric dentistry, pediatric emergency medicine, and now, pediatric gastroenterology. Our clinicians provide 30,000 patient visits annually, offering an exceptional level of care. The Pennington gift is truly a gift that keeps giving to the families in our area.” Now Being Constructed: Expanded Inpatient Care at Renown Children’s Hospital New construction of an expanded Neonatal Intensive Care Unit (NICU) with increased capacity to 49 bassinets, an expanded Pediatric Intensive Care Unit (PICU) with increased capacity to 16 private patient and family rooms, and a new Renown Children's Hospital inpatient floor with increased capacity for 38 private patient and family rooms for a total capacity of 58 pediatric beds are currently being constructed on Tahoe Tower, Level 5 of Renown Regional Medical Center. It is expected that the new units will open to patients and families in April 2023. In the most recent US News & World Report Best Hospital rankings, Renown Regional Medical Center was named as the number one hospital in Nevada. No other hospitals in the state met their stringent standards for the 2021 rankings. Renown Health is High Performing, its highest rating possible, in eight procedures and conditions including Heart Failure, Colon Cancer Surgery and Chronic Obstructive Pulmonary Disease, Hip Replacement and Knee Replacement. A hospital's score is based on multiple data categories, including patient outcomes, safety, and volumes. Hospitals earning a High Performing rating were significantly better than the national average. Renown Medical Group is an in-network provider for Hometown Health and other health plans. Drs. Gregory and Holland are pleased to see new patients at their location at the Renown Children’s Subspecialty Clinic inside Renown Regional Medical Center at 75 Pringle Way, Suite 505, Reno, Nev. Ask your pediatrician for a referral to a medical specialist when further evaluation of a particular issue is necessary. About Renown Health Renown Health is Nevada’s largest, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe, and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination, and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the locally owned not-for-profit insurance company, Hometown Health. Renown is currently enrolling participants in a community-based genetic population health study, the Healthy Nevada Project®.  About UNR Med The University of Nevada, Reno School of Medicine (UNR Med), Nevada’s first public medical school, is a community-based, research-intensive medical school with a statewide vision for a healthy Nevada. Since 1969, UNR Med has trained more than 3,900 students, residents, and fellows. UNR Med continues to improve the health and well-being of all Nevadans and their communities through excellence in student education, postgraduate training and clinical care, research with local, national and global impact and a culture of diversity and inclusion. For more information, visit med.unr.edu.

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