Search
Results for 'lab'
Clear-
Population Health Study Goes Statewide and Opens Enrollment
The study could expand to a quarter million people, making Nevada the only state in the U.S. to offer such a program. Las Vegas, Nev. (May 2, 2019) – The Healthy Nevada Project, a first-of-its-kind, community-based population health study combining genetic, clinical, environmental and social data, is expanding enrollment to Las Vegas. The Project aspires not only to offer genetic testing to every Nevadan interested in learning more about their health and genetic profile but ultimately, to develop and expand the Project for communities across the United States to drive positive health outcomes nationwide. Adding 25,000 Study Volunteers in Southern Nevada The Healthy Nevada Project is announcing a statewide expansion – opening 25,000 testing slots in Las Vegas. With southern Nevada welcoming the study, the Healthy Nevada Project will offer no-cost genetic testing through a simple spit sample to 25,000 study volunteers. Study volunteers will take Helix’s clinical-grade DNA saliva test and will receive their ancestry and traits, at no cost, through the My Healthy Nevada Traits app. Participants will then be given a chance to answer a follow-up health survey from Renown Institute for Health Innovation (Renown IHI), and upon survey completion, will be entered to win an iPhone. In addition, study participants can agree to be notified about genetic test results that could impact their health, and which could be used to improve their medical care. This return of clinical results, plus genetic counseling and other genetic services as appropriate, will be provided by Genome Medical, the leading network of clinical genetics specialists. Healthy Nevada Project’s Evolution & Ongoing Expansion With more than 35,000 study participants enrolled in just over two years, the Healthy Nevada Project has become the fastest-enrolling genetic study in the country. The Project was created by Renown IHI – a collaboration between Reno, Nev.-based not-for-profit health network, Renown Health, and the world leader in environmental data, Desert Research Institute (DRI). Leveraging Renown’s forward-thinking approach to community health care and DRI’s data analytics and environmental expertise, Renown IHI has grown its capabilities to lead a larger, more complex research study of significance that will analyze and model public health risks in Nevada and serve as a national model for future population health studies working to improve overall health through clinical care integration. During the Project’s pilot launch in September 2016, more than 10,000 community members signed up for DNA testing in just 48 hours. In March 2018, phase two offered full genomic sequencing through a simple spit test from Helix to northern Nevadans. In October 2018, the Project announced the return of clinical results for study participants, notifying them of their risk for CDC Tier 1 conditions including familial hypercholesterolemia, BRCA positive 1 and 2, and Lynch syndrome, a precursor to colon cancer. These conditions affect more than one percent of the population and are inherited so they impact family members as well. Now, the Project announced its next phase – expanding enrollment to 25,000 people in southern Nevada. Serving as a National Model This expansion to Las Vegas truly makes this the “Healthy Nevada Project” with a statewide impact making Nevada the only state in the U.S. to offer such a program. “Nevada was ripe to advance population health goals because, sadly, our state ranks near the bottom in health outcomes. The Healthy Nevada Project is working to change that,” said Anthony Slonim, M.D., DrPH, FACHE, president and CEO of Renown Health and president of Renown IHI. “Our researchers are working on a number of clinical programs and scientific studies to determine why in Washoe County, the county in which Renown Health is located, Nevada’s age-adjusted death rates for heart disease, cancer and chronic lower respiratory disease are 33 percent higher than the national rate. Imagine if we can gather more data like this on a national scale and use it to change the future of health and health care? That is what the Healthy USA Project is looking to do in the years to come.” “The Healthy Nevada Project is committed to providing study participants clinically actionable data that will help improve their health,” said Joseph Grzymski, Ph.D., associate research professor at DRI, principal investigator of the Healthy Nevada Project and chief scientific officer for Renown Health. “We are providing this information at the individual level so study volunteers can make lifesaving changes to reduce their risk. We’re also doing it on the community level to develop leading-edge research on health determinants for entire neighborhoods, states and eventually, the country.” Expanding to Become the Healthy USA Project The accelerated speed of the Project is made possible thanks to the ever-decreasing cost of sequencing. Today, Helix is able to sequence an entire exome – which allows reporting on most actionable genomic knowledge – for a fraction of what it would have cost just 10 years ago. Additionally, advances in digital health mean Helix and Project researchers can capture unprecedented amounts of health data digitally, making significant contributions to advancing precision health. The partnership has managed to remove the traditional barriers of population health studies, including the difficulty in recruiting participants, establishing quality high through put lab systems, and scaling interpretation and return of results. This development will be key as other health systems around the country join the Project. “We are thrilled to see the constant, fast-paced evolution of this Project with Renown IHI,” said Justin Kao, CoFounder of Helix. “In less than a year, we have sequenced the DNA of thousands of study participants and are now preparing to offer this incredible study in other states. Combining environmental, clinical, social and genetic data allows us to discover risk factors within communities and help people take action to live longer, healthier lives. That’s what makes the next step of the Healthy USA Project so exciting for all of us. ”Full details on study’s evolution and southern Nevada enrollment will be revealed at a press event in Las Vegas on Tuesday, May 7 at 3 p.m. Renown Institute for Health Innovation Renown Institute for Health Innovation is a collaboration between Renown Health - a locally governed and locally owned, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California; and the Desert Research Institute - a recognized world leader in investigating the effects of natural and human-induced environmental change and advancing technologies aimed at assessing a changing planet. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Learn more at https://healthynv.org/. Helix is a genomics company with a simple but powerful mission: to empower every person to improve their life through DNA. Our affordable, turnkey population health solution enables institutions to quickly scale projects that engage communities and accelerate research and discovery, ultimately allowing every person to benefit from the power of genomics. We've also created the first marketplace for DNA-powered products where people can explore diverse and uniquely personalized products developed by high-quality partners, providing powerful tools to increase engagement and speed the pace of population-scale genomics. Helix is headquartered in the San Francisco Bay Area, has an office in Denver, Colorado and operates a CLIA-certified and CAP-accredited next-generation sequencing lab in San Diego powered by Illumina (NASDAQ: ILMN) NGS technology. Helix was created in 2015. Learn more at www.helix.com. Helix, the Helix logo and Exome+ are trademarks of Helix Opco, LLC. All other trademarks referenced herein are the property of their respective owners. Additional Media Contacts: Tracy Bower DRI 702-862-5404 media@dri.edu Eric Schubert Seismic for Helix 415-939-4366 press@helix.com
Read More About Population Health Study Goes Statewide and Opens Enrollment
-
Rooted with Renown, One Families Story of Remarkable Odds
Renown Health is proud to debut our newest commercial spot, Days, on Thanksgiving Day 2022. This commercial features members of the greater northern Nevada community, former Renown patients and employees. Chris and Ann Cook are some of these community members, and we are grateful we get to tell their story. Family is everything for Chris and Ann Cook. Their loved ones span across the United States and even farther to Germany, so time spent with their children and grandchildren means the world to them. When Chris went to the emergency room for a persistent headache and drooping eye over twenty years ago, they could have never predicted the number of hours their family would spend at Renown care facilities in the coming years. “Whenever we step inside a building with that purple logo, we know right away we will be supported by friends, family and Renown staff. Our family has turned countless hours inside hospital walls into memories of gratitude for the care we receive.” Chris Cook said. “It is these memories that make us appreciate the health of our family today.” A Relationship with Renown that Spans Decades The Cooks can remember a time before Renown Regional Medical Center’s inception when Washoe Medical Center (Washoe Med) stood in its place. It was at Washoe Med that Chris received emergency brain surgery after a visit to the emergency room over 20 years ago. Immediately following a CT scan, Chris was transported to Washoe Med, now Renown Health, for emergency brain surgery and eventually to treat a hematoma. Doctors close to his case were amazed by his survival, considering Chris’ divergent situation resulting from a raisin-size colloid cyst and dissected corotated artery. He spent three weeks in the ICU recovering at the hospital, his spirits lifted by the amazing staff who brightened his day with gestures of kindness. From there, he was supported by countless friends and family members over the next three months while recovering at home. A Home Away from Home Later, the Cooks’ daughter received cancer care at Renown at the William N. Pennington Cancer Institute. Ann, Chris and their daughter found small comforts when running into the familiar faces of their daughters' past schoolmates, who are now Renown employees, in the hallways. The family became well-acquainted with the food options at Renown Regional’s Sierra Café, even finding favorites like the sushi bar. Reliable Care, Close to Home The Cooks have also experienced many happy and comforting memories at Renown and Washoe Med over the past twenty years, including the births of three of their seven grandchildren. And when Chris needed an emergency appendectomy on a Friday night four years ago, they felt confident that the best care would be received at Renown Regional Medical Center. From lab work to routine procedures or visits to urgent care, the Cooks feel rest-assured knowing Renown will be the place they can consistently trust for care with many locations close to their home in Sparks, Nevada. After spending many hours within Renown walls, Chris and Ann remarked how impressed they were by Renown Regional Medical Center’s growth in the past decade from their first encounter over twenty years ago. With a deep appreciation for the care received at Renown facilities and the technology used to help treat patients, Chris and Ann said, “We really feel confident that if something bad were to happen, you’d want to be in the care of Renown.” Family, Health and The Future "Our care at Renown has changed the course of our family’s lives and led to the success of who we are today. So, when the team at Renown approached us about participating in the commercial shoot, we knew this was meant to be the next piece in our Renown story." Chris and Ann said. "Of course, it was nice to be back at Renown, not as a patient this time, but to help the team create something great."
Read More About Rooted with Renown, One Families Story of Remarkable Odds
-
Population Genetic Screening Show to Efficiently Identify Increased Risk for Inherited Disease
Healthy Nevada Project’s community-based approach reveals up to 90% of CDC Tier 1 genetic condition risks missed using clinical care guidelines. In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke. In 2018, the Healthy Nevada Project® (the largest, community-based population health study combining genetic, clinical, environmental and social data) started notifying consenting study participants who have certain genetic variants which predispose them to the Centers for Disease Control and Prevention (CDC) Tier 1 genetic conditions. The study focused on identifying carriers of these conditions, which include Hereditary Breast and Ovarian Cancer, Lynch Syndrome, and Familial Hypercholesterolemia, because they are the most common conditions and early detection and treatment could significantly lower morbidity and mortality. Initial results from almost 27,000 study participants showed that 90% of carriers of the CDC Tier 1 genetic conditions were not previously identified in a clinical setting. The authors conclude that population genetic screening would identify at-risk carriers not identified during routine care. “Our first goal was to deliver actionable health data back to the participants of the study and understand whether or not broad population screening of CDC Tier 1 genomic conditions was a practical tool to identify at-risk individuals,” explained Joseph Grzymski, Ph.D., the principal investigator of the Healthy Nevada Project®, a research professor at the Desert Research Institute (DRI), chief scientific officer for Renown Health and lead author of the study. “Now, two years into doing that, it is clear that the clinical guidelines for detecting risk in individuals are too narrow and miss too many at risk individuals.” Within the group of 26,906 Healthy Nevada Project® participants that Grzymski’s research team studied, 358 (1.33%) were carriers for CDC Tier 1 conditions. However, only 25% of those individuals met clinical guidelines for genetic screening. Additionally, more than 20% of the carriers already had a diagnosis of disease relevant to their underlying genetic condition. “We’re at a point now where it’s possible to do clinical-grade genetic screening at population-scale,” added James Lu, M.D. Ph.D., co-founder and chief scientific officer of Helix and senior co-author of the study. “What this study demonstrates is the potential impact of doing so. By making genetic screening available more broadly, we can help the millions of Americans who are unaware that they are living at increased risk for highly actionable, genetic conditions take action.” Most notably, the study found that of the 273 participants who were carriers of the CDC Tier 1 genetic conditions and had clinical record information, only 22 individuals showed any previous suspicion of their underlying genetic conditions. “For the first time, we are providing information at the individual level so study participants can make lifesaving changes to reduce their risk based on their genetics,” said Anthony Slonim, M.D., Dr.PH., FACHE, president and CEO of Renown Health and co-director of the Project® study. “We’re conducting research on the community level to develop leading-edge research on health determinants for entire neighborhoods, states and eventually, the country. Returning these results allows us to understand the prevalence of genetically programmed diseases and illnesses that we have here in Nevada and ensure we are providing the best prevention and care plans. For the individual, the return of results can be life changing.” According to the CDC, early detection and intervention of the Tier 1 genetic conditions could have a meaningful potential for clinical action ability and a positive impact on public health. The Healthy Nevada Project®, which launched in 2016, offers free genetic testing to every Nevadan, aged 18 and older, interested in learning more about their health and genetic profile. With more than 50,000 study participants enrolled in four years, the Healthy Nevada Project® has become the fastest-enrolling genetic study in the world. For more about the Healthy Nevada Project® please visit healthynv.org Renown Institute for Health Innovation is a collaboration between Renown Health – a locally governed and locally owned, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California; and the Desert Research Institute – a recognized world leader in investigating the effects of natural and human induced environmental change and advancing technologies aimed at assessing a changing planet. Renown IHI research teams are focused on integrating personal healthcare and environmental data with socioeconomic determinants to help Nevada address some of its most complex environmental health problems; while simultaneously expanding the state’s access to leading-edge clinical trials and fostering new connections with biotechnology and pharmaceutical companies. Learn more at Healthynv.org. Helix is the leading population genomics company operating at the intersection of clinical care, research, and genomics. Its end-to-end platform enables health systems, life sciences companies, and payers to advance genomic research and accelerate the integration of genomic data into clinical care. Powered by one of the world's largest CLIA / CAP next-generation sequencing labs and its proprietary Exome+Ⓡ assay, Helix supports all aspects of population genomics including recruitment and engagement, clinically actionable disease screening, return of results, and basic and translational research. In response to the COVID-19 public health crisis, Helix has launched a sensitive and scalable end-to-end COVID-19 test system to meet the needs of health systems, employers, governments, and other organizations across the country. Learn more at www.helix.com.
-
Smart Watch Notification Saves a Life
In sailing, when you encounter rough seas, you can’t change the wind pattern, but you can adjust your sails. The same rings true for life. We confront unpredictable circumstances daily, but how we react to them can make all the difference. For Renown patient and avid sailor Robert (Dan) Seifers, recent events make this mantra reign true. A Concerning Alert Monday, Aug. 22, started out just like any other day for Dan. He was on a walk with his dog, enjoying the sunshine, when suddenly he felt a wave of dizziness and a buzz on his wrist. His Apple Watch alerted him that his heart rate had dropped to dangerous levels. Returning home immediately, he notified his wife, Carol. Doing their best not to panic, the couple confirmed the reading with their at-home blood pressure machine. The watch was right – Dan’s heart rate was in the low 30s. After taking some time to see if Dan’s heart rate would return to normal, the couple decided it was time he sought medical help. Conveniently, Carol had a lab appointment scheduled next door to Dan’s primary care physician, Dr. Bonnie Ferrara. The couple headed out the door, not realizing what the rest of the day would bring. The Next 48 Hours Upon arrival at the office, Dan calmly approached the front desk to explain his situation. With no delay, staff members sprang into action, quickly showing Dan to a patient room and notifying Dr. Ferrara. Before he knew it, Dan was receiving an electrocardiogram (EKG). Following a review of the results, Dr. Ferrara returned to let Dan know he needed to get to the hospital immediately. The rest of the afternoon moved quickly for the couple. Dr. Ferrara had already notified the Renown Regional Medical Center Emergency Room staff, who were on standby for the couple’s arrival. “Gee, this must be serious,” thought Dan, who at the time was experiencing no other alarming symptoms other than the low heart rate indicated on his watch. Several doctors and nurses began their analysis, including a chest x-ray, blood test and additional EKG. Confirming Dr. Ferrara’s results, a Renown cardiologists, Dr. Christopher Rowan and Dr. Shining Sun, joined Dan’s care team. Within two hours of checking into the hospital, Dan was admitted, monitored overnight and prepped for surgery to receive a pacemaker the next day. Tracking Your Heart Health Following the purchase of their Apple Watch devices, Dan and Carol were unaware of these heart health features. Like many others, they were looking forward to the next best tech gadget that would help them stay connected with their friends and family. Now, the couple says they will use their experience to spread the word about the importance of ensuring these settings are enabled. According to Apple, you can turn on these notifications from the Heart Rate app on your Apple Watch (Series 1 or later) to alert you to high or low heart rates and irregular heart rhythms. If you receive a notification, an irregular rhythm suggestive of atrial fibrillation (A-Fib) or a low or high heart rate has been identified and confirmed with multiple readings. In Dan’s case, the signal from his watch was the result of a heart block, a condition where the electrical signal that controls your heartbeat is partially or completely blocked. Dizziness and low heart rate are common symptoms of a heart block. But this was not the first time the couple had experienced this type of alert from their watch. More than a year and half ago, Carol’s watch notified her of an irregular heart rhythm that was suggestive of A-Fib. She immediately made an appointment with Dr. Danish Atwal, the lead cardiologist at Renown’s Helaine Greenberg Women's Heart Center. Thanks to medication prescribed by Dr. Atwal, Carol now lives a healthy, active life while managing her A-Fib, continuing to wear her Apple Watch, which can also help track her A-Fib History. “I’ll share our story with anyone who will listen and encourage them to get a smart watch. I consider myself an unofficial spokesperson,” said Carol with a chuckle. A Thankful Heart The Senior Care Plus members could not be more amazed at the way Dan was treated by the staff at Renown. “I wish I could personally thank them all. I will highly recommend Renown to all I come in contact with,” said Dan with his Apple Watch still proudly strapped to his wrist. “I was closely monitored and treated like royalty.” Quick action to medical emergencies like Dan’s is just one of the many reasons why collaboration is part of our four key values at Renown. The open line of communication between our primary care facilities and hospitals helped Dan get the prompt care he needed, right when he needed it. A month post-op, Dan is doing well and back to enjoying the things he loves during his retirement, including playing the harmonica in the Grumpy Old Man Band, exploring the northern Nevada backroads in his jeep and working on his swing at the golf course. Dan can rest assured that while enjoying the winds of life, if his heart begins to beat too slowly again, the pacemaker will send a signal to correct the beat. “The prompt attention to my heart block undoubtedly saved my life,” said Dan in what he calls his 6-star review of Renown Health. “Thank you from the bottom of my heart, which is happily beating at 60 beats per minute.” This article is not sponsored by or affiliated with Apple, Inc. For more information on the Apple Watch and it's features, visit apple.com.