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Clinical researchers with the Healthy Nevada Project co-author research paper with findings that emphasize the need for a comprehensive approach to breast cancer risk assessment – including a focus on genetic medicine – to help ensure that individuals at high risk are identified and supported proactively rather than reactively.  Breast cancer is a leading cause of cancer death among women in the United States. According to the American Cancer Society, about 1 in 8 women will develop breast cancer and about 1 in 39 women will die from breast cancer. Breast cancer is associated with increased age, hereditary factors, obesity, and alcohol use. Since 1990, breast cancer death rates have declined progressively due to advancements in treatment and detection. In Nevada there are an estimated 2,310 new breast cancer cases a year, and genetic mutations such as in the genes BRCA1 or BRCA2 remain a top risk factor for this prevalent disease. Recognizing the urgency for progress in breast cancer research, a collaborative effort between physicians, advanced practice providers and scientists from the Healthy Nevada Project® (HNP) and Helix have unveiled groundbreaking research. This study explores how genetic screenings are a necessary supplement to traditional testing methods, together offering more accurate insights into a patient's likelihood of developing breast cancer in the future. HNP is operated by Renown Genomic Medicine and the Institute for Health Innovation and is one of the largest community-based population health studies in the country. Their team works in collaboration with Helix, a leader in precision health that delivers comprehensive genomic solutions. Together, this dynamic partnership aims to understand breast cancer risk factors and pave the way for more effective preventative measures. The combined research team studied 25,591 female HNP participants to evaluate the performance of different genetic screening approaches to identify women at high risk of breast cancer. The results of this research suggest that a combined monogenic, or single-gene, and polygenic, or multi-gene, approach to breast cancer screenings helped produce more accurate results and more closely identify study participants who have a high genetic risk of developing the disease. "Based on this research, we are advocating a shift in approach which would improve breast cancer risk assessment through a combination of effective family history ascertainment and genetic screening,” said Joseph Grzymski, PhD, principal investigator of the Healthy Nevada Project, research professor at the University of Nevada, Reno School of Medicine and co-author of the breast cancer research paper. “This tailored approach, founded on the assessment of individual genetic risk, not only intends to elevate patient well-being but also will improve efficiency and equity in healthcare." Complementing the team’s research on leveraging genetics to identify women at low genetic risk of breast cancer that could safely defer mammogram screenings by five to 10 years that was released in late 2023 in JAMA Oncology, the study suggests that incorporating genetic information can assist in personalizing breast cancer screenings and optimizing the use of screening resources. "Existing disparities persist across various facets of breast cancer screening and treatment; however, genetic screening is clearly a powerful tool to help facilitate early intervention for those at higher risk,” said Jamie Schnell Blitstein, APRN, a primary care nurse practitioner at Renown Health and co-author of the breast cancer research paper. “By placing a heightened focus on risk, we underscore the pivotal role of preventative breast cancer screening.” Despite the availability of effective methods for early screening, co-authors of this research found that 78 percent of women with a family history of breast cancer had their risk ascertained only after a breast cancer diagnosis. The findings emphasize the need for a comprehensive approach to breast cancer risk assessment – including a focus on genetic medicine – to help ensure that individuals at high risk are identified and supported proactively rather than reactively.  “These findings that can profoundly impact how healthcare is delivered were only made possible by all the participants who were willing to consent to research,” said Alex Bolze, PhD from Helix and co-author of the publication. “Broad-scale collaboration projects like these between Renown Health and UNR that engage large populations where participants share both their genetic information as well as electronic health records drive advancements in preventative medicine, as well as fundamental biological research.”   The research paper was officially accepted on Jan. 29, 2024, and will be published by Elsevier, Inc. on behalf of the American College of Medical Genetics and Genomics. The contents of the paper will appear in the international journal Genetics in Medicine Open. Read the full article by visiting sciencedirect.com. The Healthy Nevada Project is currently recruiting new study participants. Free to all Nevadans with a saliva sample or blood draw, participants and their referring providers receive access to whole-exome sequencing and clinical grade results that help provide insight into their unique genetic risks tied to heart disease and certain cancers. If you are interested in enrolling in the study, schedule a Virtual Consent Appointment through MyChart or contact the Renown Institute for Health Innovation at RenownIHI@renown.org or (775) 982-6914 to be connected to a Genomic Representative. About Renown Health Renown Health is the region’s largest, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the region’s largest, locally owned not-for-profit insurance company, Hometown Health. Renown is currently enrolling participants in the largest community-based genetic population health study, the Healthy Nevada Project®. To join the Renown Health team, visit renown.org/careers. About Helix Helix is the leading population genomics and viral surveillance company operating at the intersection of clinical care, research, and data analytics. Helix enables health systems, life sciences companies, payers, and government partners to accelerate the integration of genomic data into patient care and public health decision-making. Learn more at helix.com.

Read More About Research Shows Genetic Approaches to Breast Cancer Screenings Yield More Accurate Results

Three-day medical education conference advances research, education, prevention and treatment. Physicians and medical professionals from throughout the Mountain West will soon be convening in Lake Tahoe to explore emerging treatments, the most recent advances and new clinical guidelines for the diagnosis, treatment and prevention of cardiovascular disease, diabetes mellitus, stroke and heart disease. Hosted by Renown's Institute for Heart & Vascular Health and the Nevada Academy of Family Physicians, the three-day Trends in Cardiovascular Medicine conference will bring together national experts to explore challenges and solutions to cardiovascular diseases, the leading cause of death globally, taking an estimated 17.9 million lives each year. "Our mission is to advance health in America. As Nevada's first integrated health system, with our University of Nevada, Reno School of Medicine affiliation, we are advancing health and health care through world-class medical education, clinical research and patient care for our community, our state and our nation," says Anthony D. Slonim, MD, DrPH, President & CEO, Renown Health. "And, we have so much work to do. In 2019, 9.5% of Nevadans reported being told by a health professional that they had angina or coronary heart disease; which is significantly above the national average of 8.4%. As public health and health care providers, we can do more to encourage people to adopt healthy lifestyle habits to keep their heart healthy and help prevent heart disease through the Healthy Nevada Project®, where people can understand their genetic risks at no-cost." "The driving force behind this collaborative event is the shared missions of all our organizations, across the country, to advance progress in cardiovascular research, education, prevention and treatment," says Jayson Morgan, MD, FACC, Director Cardiovascular Services at Renown. "We will be joined by colleagues from Johns Hopkins, Cedars-Sinai, Scripps, University of New Mexico Health Sciences, University of Utah, Medical College of Wisconsin, the Metabolic Institute of America and locally- with experts from Renown's Institute for Heart & Vascular Health/UNR Med, St. Mary's and Barton Health - to discuss contemporary trends in providing excellent cardiovascular care and prevention." New research will be presented each day, including: “Vaping and Electronic Cigarettes – The Hidden Epidemic: What the Clinician Needs to Know” Michael J. Blaha, MD, MPH, FACC, Professor of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Director of Clinical Research, Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, MD “Optimizing Glycemic Control in the Inpatient Setting” Kendall M. Rogers, MD, CPE, FACP, SFHM, Professor, Department of Internal Medicine, University of New Mexico School of Medicine, Chief, Division of Hospital Medicine, Department of Internal Medicine, University of New Mexico Health Sciences, Albuquerque, NM “Perioperative Medicine Update”                                                                                                                                                                                             Barbara A. Slawski, MD, MS, SFHM Professor of Medicine & Orthopaedic Surgery, Chief, Section of Hospital Medicine, Division of General Internal Medicine, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI “Understanding hATTR Amyloidosis: Clinical Presentation and Treatment Landscape” Jignesh K. Patel, MD, PhD, FACC, FRCP, FAST, FAHA, Clinical Professor of Medicine, Medical Director, Heart Transplant Program, Director, Cardiac Amyloid Program, Director, Heart Transplant Research, Cedars-Sinai Medical Center, Los Angeles, CA “Coronary Artery Calcium in 2021: Guideline-Endorsed and Ready for Prime Time” “The Evolving Landscape of Obesity Management – A 2021 Update” Ken Fujioka, MD, Director of the Center for Weight Management, Director of the Nutrition and Metabolic Research Center, Scripps Clinic, Department of Diabetes and Endocrine, San Diego, CA “The Evolving Landscape of Obesity Management – A 2021 Update” Ken Fujioka, MD, Director of the Center for Weight Management, Director of the Nutrition and Metabolic Research Center, Scripps Clinic, Department of Diabetes and Endocrine, San Diego, CA “Management of Atrial Fibrillation: Where We Are; Where We Are Headed” Matthew A. Cain, MD, Electrophysiologist, Renown Institute for Heart & Vascular Health, Renown Medical Group, Reno, NV "The Story of a Murmur” Abhilash Akinapelli, MD, Cardiac Valve & TAVR Program Director, Renown Institute for Heart & Vascular Health, Renown Medical Group, Reno, NV "Update on the Cardiovascular Effects of COVID-19” Siddharth Singh, MD, Assistant Director, Echo Fellowship Training Program, Smidt Heart Institute, Cedars-Sinai, Los Angeles, CA “Antibiotic Stewardship: How to Improve Our Prescribing for Now and Later”                                                                                                                            Valerie M. Vaughn, MD, MSc, FACP, FHM, Assistant Professor, Instructional Track Director of Hospital Medicine Research, Division of General Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT "Emerging Trends in the Clinical Management of VTE”                                                                                                                                                                Victor F. Tapson, MD, FCCP, FRCP, Director, Clinical Research for the Women’s Guild Lung Institute, Director, Venous Thromboembolism & Pulmonary Vascular Disease Research Program, Associate Director, Pulmonary and Critical Care Division, Cedars-Sinai Medical Center, Los Angeles, CA “Contemporary Approach to the Management of Diabetes as a Cardiovascular Disease”                                                                                               Yehuda Handelsman, MD, FACP, FNLA, FASPC, MACE, Medical Director & Principal Investigator, Metabolic Institute of America, Tarzana, CA The Arthur J Lurie, MD Memorial Dinner and Keynote Presentation, sponsored by the charitable Renown Foundation and the Lurie Family, is an evening ceremony to honor and memorialize the devotion and innovation of the lake Dr. Arthur J. Lurie, who personified humanitarian, medical and community service. Dr. Lurie devoted modernized heart surgery and was steadfast in his commitment to introduce new and groundbreaking techniques cardiovascular techniques to Nevada. He promoted and inspired life-changing research and advancements in heart surgery, as well as cancer research, until his passing in 1996. Medical professionals are invited to attend the 31st Annual Trends in Cardiovascular Medicine conference will take place at the Resort at Squaw Creek in Olympic Valley, CA from Friday, Nov. 5 through Sunday, Nov. 7, 2021. Those interested in registering or learning more may visit www.renown.org/trends. The clinical team at Renown Institute for Heart and Vascular Health is the recipient of a number of national awards for outstanding clinical care and service, including: In U.S. News and World Report Best Hospital rankings for 2021, Renown Regional Medical Center - #1 in the State of Nevada for 2021. No other hospital in Nevada earned recognition from U.S. News. Renown Regional Medical Center is High Performing, its highest rating possible, for Heart Failure and Chronic Obstructive Pulmonary Disease. Awarded by the American College of Surgeons for the Renown Regional earned America's 100 Best Hospitals for Critical Care Award (2021) for Superior clinical outcomes in treating pulmonary embolism, respiratory system failure, sepsis, and diabetic emergencies. Regional also earned the Pulmonary Care Excellence Award™ (2021), for superior outcomes. Designated Level II Trauma Center. For the 30th year, Renown Regional Medical Center is northern Nevada's only designated level II trauma center. Renown Regional awarded The Get with the Guidelines - Heart Failure Gold Plus Quality Achievement award for continually ensuring heart failure patients receive the most appropriate treatment according to nationally recognized, research-based guidelines, as well as AHA's mission: Lifeline Gold Receiving honor for the treatment of patients who suffer severe heart attacks. American College of Cardiology's NCDR Chest Pain-MI Registry Platinum Performance Achievement Award. Renown Regional Medical Center is one of only 225 hospitals nationwide to receive the honor. The award recognizes Renown's success in implementing a higher standard of care for heart attack patients and signifies that Renown has reached an aggressive goal of treating these patients to standard levels of care as outlined by the American College of Cardiology/American Heart Association clinical guidelines and recommendations.  To make an appointment with a provider at Renown's Institute for Heart and Vascular Health, request that your primary care provider make a referral. For more information on Renown's Institute for Heart and Vascular Health, visit renown.org/Health-Services/Heart-Care.     About Renown Health Renown Health is a locally governed, not-for-profit integrated healthcare network serving northern Nevada, Lake Tahoe and northeast California. In U.S. News and World Report Best Hospital rankings, Renown Regional Medical Center was listed #1 in the State of Nevada. Renown has a long tradition and commitment to improve the care and the health of our community. For more information, visit renown.org.

Read More About Leading Experts Convene in Tahoe to Focus on Scientific Advancements and the Prevention of Cardiovascular Disease, the #1 Cause of Death Globally

Renown Children’s Hospital pediatric ophthalmologist Dr. Mitchell Strominger hosts state-wide virtual event to provide routine vison screenings for children and Walk with a Doc. Renown Children’s Hospital pediatric ophthalmologist Dr. Mitchell Strominger is set to host a virtual Walk with a Doc event on Sunday, June 14 at 10 a.m. for elementary school children and their parents. During this free event, Dr. Strominger will give a brief, kid-friendly talk about the importance of routine vision screenings and show parents how to conduct a vision screening with their kids at home. He will close out the morning session with a live Q&A. Following the event, families are encouraged to get outside and enjoy a walk in the great outdoors. The event is sponsored by Renown Children’s Hospital and free to participants, however you must register to receive the link to attend. “Vision is important for learning, experiencing new things and interacting with others, which is why it’s critical for children to get vision screenings early and routinely,” said Dr. Strominger. “The best time to screen a child’s vision is kindergarten through third grade as the cells in the brain responsible for vision are continuously developing up until age eight. If we detect vision problems early, we here at Renown Children’s Hospital have the expertise and technology to correct these vision problems and enable children to live healthy, productive lives.” Individuals who register for this event will be emailed a vision-screening sheet to help facilitate an at-home screening, as well as a form to send back to their child’s pediatrician or pediatric ophthalmologist upon completion to determine the best course of action. Dr. Strominger added, “Many parents and schools have put off vision screenings due to COVID- 19 school closings, hesitations of safely leaving their homes or potential financial costs. I am pleased to host this virtual event on behalf of Renown Children’s Hospital, to engage kids and parents in a conversation on the importance of vision and to remind the community that we are here to help and provide the care they need, both in-person and virtually—be it over a smart phone, tablet or computer screen.” This virtual event will take place in the newly renovated Fianna’s Healing Garden which re-opens later this month and has been funded 100% by donations through the Renown Health Foundation. Located in the heart of Renown Regional Medical Center, the healing garden serves as place to enjoy the serenity and beauty of the outdoors. Dr. Strominger is one of 26 pediatric subspecialists recruited to Renown Children’s Hospital since 2016, thanks to the Pennington Foundation's $7.5 million donation made to the non-profit Renown Health Foundation to expand children’s health services. June marks the four-year anniversary of the Nevada Chapter of the American Academy of Pediatrics’ (Nevada APP) participation in the national Walk with A Doc event. Dr. Strominger is the secretary and treasurer for the Nevada AAP. From pediatric specialties, 24/7 ER care and surgery, to imaging, pediatric ICU and child life specialists, Renown Children’s Hospital is dedicated to helping kids feel welcome, safe and well cared for. Through each visit, parents can expect the highest level of care for their child’s health and well-being from birth and beyond. To support Renown Children’s Hospital and help local children in need get access to vital health services like routine vision screenings, please visit the Renown Health Foundation.     About Renown Health Renown Health is a locally governed and locally owned, not-for-profit integrated healthcare network serving northern Nevada, Lake Tahoe and northeast California. Renown is one of the region’s largest private employers with a workforce of more than 7,000. It comprises three acute care hospitals, Renown Children’s Hospital, Renown Rehabilitation Hospital, the area’s most comprehensive medical group and urgent care network, and the region’s largest and only locally owned not-for-profit insurance company, Hometown Health. Renown has a long tradition and commitment to continually improve the care and the health of our community. For more information, visit renown.org.

Read More About Elementary Schoolers: Take Part in Free Virtual Vision Screening

Renown Health's Dr. Christopher Rowan recently joined a distinguished panel of experts on the "Game Changers in Medicine" podcast to discuss the science behind the discovery of warfarin. Renown Health Cardiologist Dr. Christopher Rowan was just featured on an episode of Game Changers in Medicine, a groundbreaking medical history podcast from Dramatic Health about some of the world’s most significant medical discoveries. The episode, Warfarin: How a rat poison became one of the world's most widely prescribed drugs, dives into the fascinating history of Warfarin and its life-saving effects on humans.  During the episode, Dr. Rowan, whose research focus is heart disease and atherosclerosis, is joined by experts Kevin Walters, Historian and Strategic Research Coordinator at the Wisconsin Alumni Research Foundation (WARF); and Ramya M. Rajagopalan, Ph.D. of the Institute for Practical Ethics at UC San Diego. Listen to the episode now or download it wherever you listen to podcasts.  History of Warfarin Warfarin prevents blood clots from forming or expanding. The drug is especially important for individuals who have experienced a heart attack or stroke, or are at risk of experiencing either. However, the backstory of the drug is rather fascinating.  Beginning in the 1920s, an unknown disease was killing cattle throughout the U.S. and Canada. Desperate to find a solution, one farmer drove 200 miles to the University of Wisconsin with a dead cow, bales of spoiled hay and a milk can of unclotted blood in tow. He crossed paths with a scientist, whose team set out to determine the hemorrhagic component of the spoiled hay, resulting in a series of medical discoveries that would revolutionize medicine.  After learning more about Warfarin and how Vitamin K could reverse its blood thinning properties, doctors first prescribed the drug for human use in 1954. It is perhaps most widely known for saving President Dwight D. Eisenhower after he suffered a heart attack in 1955. Today, Warfarin continues to saves millions of lives each year. “Before blood thinners like Warfarin, people would experience strokes, blood clots in their lungs, blood clots in their legs, blood clots in their hearts, along with countless other clotting disorders - these conditions likely cutting their lifespans short,” Dr. Rowan said during the podcast. “Warfarin revolutionized the treatment of patients who suffer from heart attacks and strokes, helping them to live normal and healthy lives. The drug changed medicine forever and helped make incredible innovations such as mechanical heart valves a reality.” Interview Opportunity Dr. Rowan is available for interviews to discuss the importance of this unique medical discovery and the positive impact it has on many of the patients he treats every day. Please email news@renown.org or call 775-691- 7308 to coordinate an interview.      About Renown Health Renown Health is the region’s largest, locally owned and governed, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the region’s largest, locally owned not-for-profit insurance company, Hometown Health. Renown’s institute model addresses social determinants of health and includes: Child Health, Behavioral Health & Addiction, Healthy Aging and Health Innovation. Clinical institutes include: Cancer, Heart and Vascular Heath, Neurosciences and Robotic Surgery. Renown is currently enrolling participants in the world’s largest community-based genetic population health study, the Healthy Nevada Project® . For more information, visit renown.org. About Dramatic Health Dramatic Health, a national healthcare video company, is the producer of the six-part podcast series Game Changers in Medicine. The series premiered in July with an episode about Vitamin K and an enterprising Boston house doctor. The August episode showcased the creation of a smallpox vaccine and its parallels to today's urgent search for a COVID-19 vaccine. Game Changers in Medicine ranked #27 in Apple Podcasts: Life Sciences in the United States according to Chartable as of August 21, 2020. Both episodes, a series backgrounder, and additional material about the podcast series are available at www.gamechangersinmedicine.com and can be accessed wherever you listen to podcasts.

Read More About Renown Cardiologist Shares Insight on Warfarin

Pictured left to right: Erin VanKirk, MSN, RN, Renown Health Director of Nursing Education; Mitch Krebs, Program Director at Helmsley Charitable Trust; Dr. Graf, Renown Health CEO; Greg Walaitis Renown Health Chief Development Officer. Renown Health will use the grant to build the Helmsley Simulation and Innovation Center to improve the health system’s training abilities The Leona M. and Harry B. Helmsley Charitable Trust has granted $3.1 million to Renown Health for construction of a new simulation and innovation center that will greatly expand the health system’s ability to train healthcare providers throughout northern Nevada. The new center will be named the Helmsley Simulation and Innovation Center. Expected to open in April 2023, the center will feature three simulated patient rooms, classroom space, computer labs and a conference center, allowing trainers to run current and future healthcare professionals through real-life acute, outpatient, telemedicine and specialty care scenarios. The new center will let Renown Health train substantially more nurses, physicians, community clinical partners, medical students and rural providers while improving medical and nursing expertise to support staff throughout northern Nevada. “The Helmsley Charitable Trust is excited to fund this new simulation center, which will provide healthcare professionals across rural Nevada with state-of-the-art training in a variety of situations they’ll encounter,” said Walter Panzirer, a trustee of the Helmsley Charitable Trust. “The project fits with our goal to level the playing field by giving rural residents access to top-notch healthcare, regardless of their ZIP code.” “Simulation education has become standard practice for many of our healthcare personnel,” said Erin Van Kirk MSN, RN, Director of Nursing Education. “This lab will provide expanded opportunities in a controlled setting where physicians, nurses, and students can gain valuable experience in providing the best care possible.” Renown Health has outgrown its current simulation lab, which opened in 2016 in Renown Regional Medical Center. The new, larger, state-of-the-art simulation and innovation center will increase Renown Health’s training capacity from 1,500 to 2,500 each year. The new facility will be equipped with state-of-the-art simulation mannequins and other equipment that includes a telemetry monitor, IV and epidural equipment, a code cart, a defibrillator, a balloon pump, ventilators and a cooling machine. The center will also support Renown Health’s recently established partnership with the University of Nevada, Reno School of Medicine, expanding training modules focused on rural health and virtual care through telemedicine. “The facility will help Renown Health respond to our region’s growing population by allowing us to support the training and competency necessary for our care providers to make a genuine difference in the health and well-being of the people and communities we serve,” said Melodie Osborn, RN, MBA, Chief Nursing Executive at Renown Health. “This generous grant for the new simulation and innovation center from the Helmsley Charitable Trust is truly an investment in the bright future we envision for Renown, our care teams and the community.” About Renown Health Renown Health is the region’s largest, locally governed, not-for-profit integrated healthcare network serving Nevada, Lake Tahoe and northeast California. With a diverse workforce of more than 7,000 employees, Renown has fostered a longstanding culture of excellence, determination and innovation. The organization comprises a trauma center, two acute care hospitals, a children’s hospital, a rehabilitation hospital, a medical group and urgent care network, and the region’s largest, locally owned not-for-profit insurance company, Hometown Health. Renown is currently enrolling participants in the world’s largest community-based genetic population health study, the Healthy Nevada Project®. For more information, visit renown.org. About the Helmsley Charitable Trust The Leona M. and Harry B. Helmsley Charitable Trust aspires to improve lives by supporting exceptional efforts in the U.S. and around the world in health and select place-based initiatives. Since beginning active grantmaking in 2008, Helmsley has committed more than $3 billion for a wide range of charitable purposes. Helmsley’s Rural Healthcare Program funds innovative projects that use information technologies to connect rural patients to emergency medical care, bring the latest medical therapies to patients in remote areas, and provide state-of-the-art training for rural hospitals and EMS personnel. To date, this program has awarded more than $500 million to organizations and initiatives in the states of North Dakota, South Dakota, Nebraska, Wyoming, Minnesota, Iowa, Montana, and Nevada. For more information, visit helmsleytrust.org.

Read More About Helmsley Charitable Trust Grants $3.1 Million to Renown Health