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  3. NRG-LU008

Addition of High Dose, Targeted Radiation for Locally-Advanced Inoperable Non-small Cell Lung Cancer

Short Title: NRG-LU008


Enrollment Status: Recruiting

NCT #: NCT05624996

Specialty Area: Oncology

Condition Studied: Locally Advanced, Inoperable Non-Small Cell Lung Cancer (NSCLC)

Age Groups: Adult; Older Adult

Phase: III


Study Information

Summary / Purpose

To find out if adding high-dose, targeted radiation (SBRT) to the usual treatment helps people with inoperable lung cancer live longer or respond better to treatment.

Study Type: Interventional
Accepts Healthy Volunteers: No

Who Can Participate

Eligibility Criteria:
  • Adults 18+ years of age
  • Diagnosed with stage IIB or III Non-Small Cell Lung Cancer (NSCLC)
  • Cancer must have moved into nearby tissue (locally advanced) and cannot be removed by surgery (unresectable)
  • Must be eligible to receive chemotherapy, radiation, and immunotherapy

What's Involved

Participation in the study will include:
  • Treatment with image-guided radiation therapy (IGRT), chemotherapy, and immunotherapy with or without high-dose targeted radiation (SBRT)
  • Chemotherapy may include: cisplatin, carboplatin, paclitaxel, nab-paclitaxel, pemetrexed, or etoposide given intravenously (IV)
  • Immunotherapy may include: durvalumab given intravenously (IV) or osimertinib given orally
  • CT scans and PET scans to monitor response to treatment
  • Blood and tissue sample collection to monitor your health and treatment effects
  • Questionnaires

Principal Investigator

Additional Information

Location: Renown Health, Office of Clinical Research
Address:

1500 E 2nd St. Reno, NV 89502

General Research: 775-982-3646
Oncology Research: 775-982-5050
Email: Renown-CRD@renown.org

Complete Study Details: https://clinicaltrials.gov/study/NCT05624996

Disclaimer: This listing gives you general information about the study and isn't part of the official consent process. If you decide to learn more, the research team will talk with you and check if you meet any additional requirements to join the study.

ER Wait Times

How are wait times calculated?

Our estimated ER wait times reflect the average time from check-in to being seen by a medical professional during triage, where patients are prioritized based on the severity of their condition.

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