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Sacituzumab Tirumotecan in People With Breast Cancer

Short Title: MK-2870-032


Enrollment Status: Recruiting

NCT #: NCT06966700

Specialty Area: Oncology

Conditions Studied: Early Stage; High-Risk Breast Cancer

Age Groups: Adult; Older Adult

Phase: III


Study Information

Summary / Purpose

To find out if adding sacituzumab tirumotecan to pembrolizumab and chemotherapy helps eliminate cancer cells before surgery and improves long-term outcomes for people with high-risk, early-stage triple-negative or HR-low positive/HER2-negative breast cancer.

Study Type: Interventional
Accepts Healthy Volunteers: No

Who Can Participate

Eligibility Criteria:
  • Adults 18+ years of age
  • Diagnosed with high-risk, early-stage breast cancer
  • Cancer must be located in the breast or nearby lymph nodes

What's Involved

Participation in the study will include:
  • Sacituzumab tirumotecan (Sac-TMT), pembrolizumab, and chemotherapy
  • Surgery to remove the tumor and lymph nodes
  • CT/MRI scans to check response to treatment
  • Blood and urine tests to monitor your health and treatment effects
  • Electrocardiogram (ECG) to monitor heart function
  • Questionnaires

Principal Investigator

Additional Information

Location: Renown Health, Office of Clinical Research
Address:

1500 E 2nd St. Reno, NV 89502

General Research: 775-982-3646
Oncology Research: 775-982-5050
Email: Renown-CRD@renown.org

Disclaimer: This listing gives you general information about the study and isn't part of the official consent process. If you decide to learn more, the research team will talk with you and check if you meet any additional requirements to join the study.

ER Wait Times

How are wait times calculated?

Our estimated ER wait times reflect the average time from check-in to being seen by a medical professional during triage, where patients are prioritized based on the severity of their condition.

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